Investigating the networks of brain regions that govern different kinds of memory
Research by using magnetic resonance imaging
Memory is the result of groups of brain regions working together
We investigate the networks of brain regions that govern different kinds of memory. We know that memory is not localized to single brain regions, but instead is the result of groups of brain regions working together. To do this we examine the effect of changes to specific regions of the brain on the whole network, and correlate these network changes with behavior. We also work on the role of neurochemicals, such as acetylcholine, in memory. We accomplish this research by using magnetic resonance imaging in animal models, to look at changes in structure, function and connections – and by combining it with behavioral assessments.
Kumar V, Croxson PL, Simonyan K (2016) Structural Organization of the Laryngeal Motor Cortical Network and Its Implication for Evolution of Speech Production. J Neurosci 36: 4170-4181
Halene TB, Kozlenkov A, Jiang Y, Mitchell AC, Javidfar B, Dincer A, Park R, Wiseman J, Croxson PL, Giannaris EL, Hof PR, Roussos P, Dracheva S, Hemby SE, Akbarian S (2016) NeuN(+) neuronal nuclei in non-human primate prefrontal cortex and subcortical white matter after clozapine exposure. Schizophr Res 170: 235-44
Mars RB, Foxley S, Verhagen L, Jbabdi S, Sallet J, Noonan MP, Neubert F-X, Andersson JL, Croxson PL, Dunbar RIM, Khrapichev AA, Sibson N, Miller KL, Rushworth MF (2015) The extreme capsule fiber complex in humans and macaque monkeys: A comparative diffusion MRI tractography study. Brain Struct Funct 221: 4059-4071
Croxson PL, Walton ME, Boorman ED, Rushworth MF, Bannerman DM (2014) Unilateral medial frontal cortex lesions cause a cognitive decision-making deficit in rats. Eur J Neurosci [epub ahead of print]
Baxter MG, Croxson PL (2013) Behavioral control by the orbital prefrontal cortex: reversal of fortune. Nat Neurosci 16:984-985
O’Reilly JX, Croxson PL, Jbabdi S, Sallet J, Noonan MP, Mars RB, Browning PG, Wilson CR, Mitchell AS, Miller KL, Rushworth MF, Baxter MG (2013) Causal effect of disconnection lesions on interhemispheric functional connectivity in rhesus monkeys. Proc Natl Acad Sci U S A. 110:13982-139877
Croxson PL, Baxter MG (2012) Facing the role of the amygdala in emotional information processing. PNAS 109:21180-21181
Croxson PL, Browning PGF, Gaffan D, Baxter MG (2012) Acetylcholine facilitates recovery of episodic memory after brain damage. J Neurosci 32: 13787-13795
Meet the Team
Postdoctoral Research Fellow
Joseph Simon IV
High School Student Volunteer
Graduate and Postdoctoral Positions
Thank you for your interest in the Croxson Lab. Unfortunately, at this time there are no positions available, but please check back in the future. If you are interested in pursuing M.Sc. or Ph.D. studies in the lab, please send an email.
News & Outreach
Awards — November 2016
Paula Croxson and Mark Baxter awarded an R21: “Chemogenetic interrogation of large-scale functional connectivity networks”
The Art of Storytelling — November 2016
Paula Croxson and Daniela Schiller host “The Art of Storytelling” at the Society for Neuroscience Cognitive Neuroscience Social
Best Poster award at the Brain Imaging Center Annual Symposium — October 2016
Joseph Simon awarded Best Poster award at the Brain Imaging Center Annual Symposium
NARSAD Young Investigator Grants — August 2016
– Paula Croxson awarded Brain and Behavior Research Foundation NARSAD Young Investigator Grant: “Longitudinal assessment of the cognitive and molecular risk factors underlying psychosis.”
Travel Award Winners — October 2016
Jamie Nagy, Sean Walsh and Christienne Damatac awarded Travel Awards to the Persistent Maladaptice Behaviors conference in Rochester, NY!
Richard and Susan Friedman Research Scholar Award — December 2015
Paula Croxson and Gordon Xu awarded Richard and Susan Friedman Research Scholar Award for collaborative research project: ‘Exploring the functional and metabolicspinal cord.”
Sean Walsh article publication in Journal of Neuroscience — December 2015
Sean Walsh’s article published in Journal of Neuroscience! “Very Early Brain Damage Leads to Remodeling of the Working Memory System in Adulthood: A Combined fMRI/Tractography Study.”
Story Collider “How Cold is too Cold?” — September 2016
How Cold is too Cold? Neuroscientist Paula Croxson is determined to finish her first open-water swimming race — despite the dangers.
Pint of Science “The Art of Perception” — March 2016
At this brain-inspired Pint of Science event, Paula Croxson will discuss how memory helps the brain interpret, and sometimes misinterpret, the signals it receives from the outside world. Other resources.
Story Collider Mount Sinai show “Studying the Brain” — March 2016
This special Story Collider show was hosted in partnership with the Friedman Brain Institute at Mount Sinai. From the tragic to the hilarious, it explored the deeply human side of brain research.
The Unexpected Benefits of Science Outreach — March 2015
An essay on one researcher’s experience telling a story at The Story Collider.
Paula Croxson interviewed on CBS local — 2014
Possibility Of Erasing Bad Memories Moves Closer Toward Reality, CBS interview with Paula Croxson
Story Collider “When Your Grandmother Forgets Who You Are” — March 2013
When Paula Croxson began to study memory as a neuroscientist, she also learned a new way of thinking about her grandmother’s failing memory. Listen.