Benson Lab

Synapses in Development and Disease

Research

We are interested in how neural circuits form and how they can be made vulnerable to disease or become modified to generate symptoms. To do this the lab incorporates a multidisciplinary approach to study the generation and function of neural circuits in mouse models relevant to human disease. Our recent work has focused on three main areas. The first employs microscopy and super-resolution strategies to examine cellular mechanisms driving synapse formation and regulating synapse composition. The second relates these cellular phenomena to cell function and behavior; and the third strategy examines coordinated actions between nervous and immune systems. These approaches are currently being employed in order to identify rules and patterns important for establishing corticostriatal circuits relevant to neurodevelopmental disorders and to test how the same circuits expressing gene mutations relevant to Parkinson’s disease respond differently to stressful experiences and may even generate an environment more supportive for tumor growth and metastasis.  

Contact Us

Benson Laboratory
Deanna Benson, PhD
Professor, Neuroscience
Location
Lab: HESS 9-302
Office: HESS 9-114
Phone
Office: 212.824.8974
Fax: 212.659.8510
Email

Publications

Meet the Team

Abhishek Sahasrabudhe

Abhishek Sahasrabudhe

Postdoctoral Fellow

Christopher Guevara

Christopher Guevara

PhD Student

Ajay Tupil

Ajay Tupil

Associate Researcher

Roxana Mesias

Roxana Mesias

PhD Student

Ayan Hussein

Ayan Hussein

PhD Student

Pamela Del Valle

Pamela Del Valle

PhD Student

Alexander Tielemans

Alexander Tielemans

Master's Student

Swati Gupta

Swati Gupta

Postdoctoral Fellow

Kyomi Blake

Kyomi Blake

Undergraduate

Fatema Begum

Fatema Begum

Undergraduate

Oneli Ranasinghe

Oneli Ranasinghe

Undergraduate

Kumayl Alloo

Kumayl Alloo

High School Senior

Emily Dodd

Emily Dodd

High School Senior

Kelly Turner

Undergraduate

LAB ALUMNI (Current Position)

Bridget Matikainen-Ankney, PhD (Postdoctoral Fellow, Washington University)
Nebojsa Kezunovic, PhD (Medical Science Liason, Amgen)
Cynthia Mercedes, MS (Clinical Research Assoc, Mount Sinai)
Lauren Friedman, PhD (Director, Scientific Affairs, Alzheimer’s Drug Discovery Association)
Chenel Morrison, BS (Medical Student, Cornell-Weill)
Frances Williams, MPH (Graduate Research Asst, Columbia)
Ellen Hoffman, MD, PhD, (Asst Professor, Yale Child Study Center)
Bryan Sepulveda, MS, PhD (Director, Medical Affairs & Scientific Comm, Audentes Therapeutics)
Kuangfu Hsiao, PhD  (Postdoctoral Fellow, Rockefeller Univ)
Caitlin Trasande, PhD (Scientific Director, Sr Program Manager, Sloan-Kettering)
Ioana Carcea, MD, PhD (Asst Professor, Rutgers University, Brain Health Institute)
Pamela Shah/Mukhatiyar, BS, MD (Asst Professor, Pediatrics, Rutgers NJ Medical School)
Eva Chmielnicki, PhD (Director of Business Development, Bristol Meyers Squibb)
Tonya Anderson, PhD (Medical Science Consultant & Patient Advocate/Liason)
C. David Mintz, MD, PhD (Assoc Professor, Johns Hopkins)
Iddil Bekirov, PhD (Program Manager, OTDC, NIMH)
Tracey Dickson, PhD (Assoc. Dean, College of Health and Medicine, Univ of Tasmania, Australia)
Wandong Zhang, PhD (Senior Scientist, BioMarin Pharmaceutical)