Research

The focus of the Huntley lab is on understanding how abnormal neural circuit development impacts synaptic and behavioral functions later in life. Current research projects use mouse models to investigate the impact of Parkinson’s risk gene mutations on development and synaptic plasticity of prefrontal corticostriatal connectivity and how such mutation-driven cortical and striatal circuit alterations generate prevalent PD-associated non-motor symptoms such as cognitive abnormalities and psychiatric-like behaviors.