Huntley Lab

Laboratory of Synaptic Circuit Development and Plasticity

Research

The focus of the Huntley lab is on understanding how abnormal neural circuit development impacts synaptic and behavioral functions later in life. Current research projects use mouse models to investigate the impact of Parkinson’s risk gene mutations on development and synaptic plasticity of prefrontal corticostriatal connectivity and how such mutation-driven cortical and striatal circuit alterations generate prevalent PD-associated non-motor symptoms such as cognitive abnormalities and psychiatric-like behaviors.

Contact Us

Huntley Laboratory
George W. Huntley, Ph.D
Professor
Department of Neuroscience and the Friedman Brain Institute
Director, Neuroscience PhD Graduate Training Area
Ombuds for the Graduate School of Biomedical Sciences
Icahn School of Medicine at Mount Sinai
Location
Lab: HESS CSM 9-302
Office: HESS CSM 9-108
Phone
Office: 212.824.8981
Lab: 212.824.9133
Fax: 212.537.9583
Email

Cajal-Retzius neuron in Layer 1 of developing neocortex labeled with antibodies to calbindin

Publications

For a complete list of Huntley lab publications, please click here.https://pubmed.ncbi.nlm.nih.gov/?term=Huntley+GW&sort=date

Meet the Team

Pamela del Valle

PhD student

Pamela is a PhD student in the Neuroscience graduate program using mouse models to investigate how the Parkinson’s disease-linked LRRK2-G2019S mutation impacts melanoma growth.

Swati Gupta

Instructor

Swati is an Instructor studying mechanisms by which Parkinson’s-related mutations impact AMPAR subunit trafficking and synapse plasticity.

Alexander Tielemans

PhD student

Xander is a PhD student studying how Parkinson’s mutations modify intracellular trafficking pathways in striatal and cortical neurons.

Ally Magee

PhD student

Nate Westneat

Lab technician

Nate is our laboratory technician who contributes to and oversees…. everything!