Rich Lab

Neurophysiology of Affect and Cognition


erin rich headshotEstimates of how good or bad something will be influence how we experience the world, impacting our actions, choices, attention and memory. Our lab is interested in how the brain processes affective information, in other words the “goodness” or “badness” of experiences, and how this interacts with cognitive processes. Our studies combine hypothesis-driven behavioral designs with large-scale neurophysiological recordings to understand how neural dynamics give rise to behavior and cognition.

Contact Us

Rich Laboratory
Erin L Rich, MD, PhD
Assistant Professor, Neuroscience
Office: HESS CSM 10-115
Office: 212.824.9304



natneuro jul2016 coverDecoding subjective decisions from orbitofrontal cortex.
Rich EL, Wallis JD.
Nat Neurosci. 2016 Jul;19(7):973-80. doi: 10.1038/nn.4320. Epub 2016 Jun 6. PMID 27273768

What stays the same in orbitofrontal cortex.
Rich EL, Wallis JD.
Nat Neurosci. 2016 May 26;19(6):768-70. doi: 10.1038/nn.4305. No abstract available.PMID: 27227365. (this is a commentary)


Medial-lateral organization of the orbitofrontal cortex.
Rich EL, Wallis JD.
J Cogn Neurosci. 2014 Jul;26(7):1347-62. doi: 10.1162/jocn_a_00573. Epub 2014 Jan 9. PMID: 24405106


Prefrontal-amygdala interactions underlying value coding.
Rich EL, Wallis JD.
Neuron. 2013 Dec 18;80(6):1344-6. doi: 10.1016/j.neuron.2013.11.027. PMID: 24360539
(this is a commentary)


jpsychres coverStriatal activity in borderline personality disorder with comorbid intermittent explosive disorder: sex differences.
Perez-Rodriguez MM, Hazlett EA, Rich EL, Ripoll LH, Weiner DM, Spence N, Goodman M, Koenigsberg HW, Siever LJ, New AS.
J Psychiatr Res. 2012 Jun;46(6):797-804. doi: 10.1016/j.jpsychires.2012.02.014. Epub 2012 Mar 29. PMID: 22464337


Challenges of Interpreting Frontal Neurons during Value-Based Decision-Making.
Wallis JD, Rich EL.
Front Neurosci. 2011 Nov 22;5:124. doi: 10.3389/fnins.2011.00124. eCollection 2011. PMID: 22125508

2009 & earlier

jneurosci jun2009 coverRat prefrontal cortical neurons selectively code strategy switches.
Rich EL, Shapiro M.
J Neurosci. 2009 Jun 3;29(22):7208-19. doi: 10.1523/JNEUROSCI.6068-08.2009. PMID: 19494143

jneurosci sept2008 coverThe neurotrophin-inducible gene Vgf regulates hippocampal function and behavior through a brain-derived neurotrophic factor-dependent mechanism.
Bozdagi O, Rich E, Tronel S, Sadahiro M, Patterson K, Shapiro ML, Alberini CM, Huntley GW, Salton SR.
J Neurosci. 2008 Sep 24;28(39):9857-69. doi: 10.1523/JNEUROSCI.3145-08.2008. PMID: 18815270

Prelimbic/infralimbic inactivation impairs memory for multiple task switches, but not flexible selection of familiar tasks.
Rich EL, Shapiro ML.
J Neurosci. 2007 Apr 25;27(17):4747-55. PMID: 17460087

Meet the Team

Feng-Kuei Chiang

Feng-Kuei Chiang

Postdoctoral Fellow

I am interested in cognitive functions of prefrontal cortex, which include working memory, hierarchical learning, and decision-making. Mainly, how prefrontal areas dynamically encode a series of actions/events under the sequential or hierarchical tasks.

feng-kuei.chiang (at) mssm (dot) edu

Pierre Enel

Pierre Enel

Postdoctoral Fellow

Computational modeling of decision networks

pierre.enel (at) mssm (dot) edu

Zach Gillis

Zach Gillis

Research Assistant

zachary.gillis (at) mssm (dot) edu

Funding & Awards

K08 Mentored Clinical Scientist Research Development Award (NIDA, DA039351)